8FW5

Chimeric HsGATOR1-SpGtr-SpLam complex

Summary for 8FW5

Entry DOI	10.2210/pdb8fw5/pdb
EMDB information	29497
Descriptor	GATOR complex protein DEPDC5, GUANOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... (12 entities in total)
Functional Keywords	mtor complex 1 (mtorc1), rag gtpase, gtr gtpase, lamtor, gator1, nutrient sensing, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	9
Total formula weight	451146.47
Authors	Tettoni, S.D.,Egri, S.B.,Doxsey, D.D.,Ouch, C.,Chang, J.,Song, K.,Xu, C.,Shen, K. (deposition date: 2023-01-20, release date: 2023-07-26, Last modification date: 2023-09-20)
Primary citation	Tettoni, S.D.,Egri, S.B.,Doxsey, D.D.,Veinotte, K.,Ouch, C.,Chang, J.Y.,Song, K.,Xu, C.,Shen, K. Structure of the Schizosaccharomyces pombe Gtr-Lam complex reveals evolutionary divergence of mTORC1-dependent amino acid sensing. Structure, 31:1065-1076.e5, 2023 Cited by PubMed: 37453417 DOI: 10.1016/j.str.2023.06.012 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.08 Å)

Structure validation