8FML
Cryo-EM structure of NLR family apoptosis inhibitory protein 5 (NAIP5) in complex with a full-length flagellin (FliC) ligand
Summary for 8FML
Entry DOI | 10.2210/pdb8fml/pdb |
EMDB information | 29296 |
Descriptor | Baculoviral IAP repeat-containing protein 1e, Flagellin (2 entities in total) |
Functional Keywords | inflammasome, innate immunity, bacterial ligand, host-pathogen interaction, protein complex, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 213742.57 |
Authors | |
Primary citation | Paidimuddala, B.,Cao, J.,Zhang, L. Structural basis for flagellin-induced NAIP5 activation. Sci Adv, 9:eadi8539-eadi8539, 2023 Cited by PubMed: 38055825DOI: 10.1126/sciadv.adi8539 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.93 Å) |
Structure validation
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