8DU5

Murine sialidase-1 (NEU1)

Summary for 8DU5

Entry DOI	10.2210/pdb8du5/pdb
Descriptor	Sialidase-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	sialic acid, sialidase, glycosidase, lysosome, hydrolase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	85734.37
Authors	Gorelik, A.,Illes, K.,Nagar, B. (deposition date: 2022-07-26, release date: 2023-05-31, Last modification date: 2023-10-25)
Primary citation	Gorelik, A.,Illes, K.,Mazhab-Jafari, M.T.,Nagar, B. Structure of the immunoregulatory sialidase NEU1. Sci Adv, 9:eadf8169-eadf8169, 2023 Cited by PubMed: 37205763 DOI: 10.1126/sciadv.adf8169 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation