8DU5

Murine sialidase-1 (NEU1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Sialidase-1	polymer	378	41582.5	2	UniProt (O35657) In PDB	Mus musculus (house mouse)	G9 sialidase,Lysosomal sialidase,N-acetyl-alpha-neuraminidase 1
2	C	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
3	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
4	E	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, B: 42 - 409 (UniProt: O35657)

PDB	External Database	Details
Asp 32	-	expression tag
Arg 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
Gly 40	-	expression tag
Ser 41	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83165.0
Branched	Number of molecules	3
	Total formula weight	1905.8
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	85734.4

*Water molecules are not included.