8DU5

Murine sialidase-1 (NEU1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004308	molecular_function	exo-alpha-sialidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005764	cellular_component	lysosome
A	0005765	cellular_component	lysosomal membrane
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0006689	biological_process	ganglioside catabolic process
A	0009313	biological_process	oligosaccharide catabolic process
A	0009986	cellular_component	cell surface
A	0010976	biological_process	positive regulation of neuron projection development
A	0016020	cellular_component	membrane
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016997	molecular_function	alpha-sialidase activity
A	0030054	cellular_component	cell junction
A	0031410	cellular_component	cytoplasmic vesicle
A	0043202	cellular_component	lysosomal lumen
A	2000291	biological_process	regulation of myoblast proliferation
B	0004308	molecular_function	exo-alpha-sialidase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005764	cellular_component	lysosome
B	0005765	cellular_component	lysosomal membrane
B	0005886	cellular_component	plasma membrane
B	0006629	biological_process	lipid metabolic process
B	0006689	biological_process	ganglioside catabolic process
B	0009313	biological_process	oligosaccharide catabolic process
B	0009986	cellular_component	cell surface
B	0010976	biological_process	positive regulation of neuron projection development
B	0016020	cellular_component	membrane
B	0016042	biological_process	lipid catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016997	molecular_function	alpha-sialidase activity
B	0030054	cellular_component	cell junction
B	0031410	cellular_component	cytoplasmic vesicle
B	0043202	cellular_component	lysosomal lumen
B	2000291	biological_process	regulation of myoblast proliferation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Repeat: {"description":"BNR 1"}

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site_id	SWS_FT_FI2
Number of Residues	22
Details	Repeat: {"description":"BNR 2"}

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site_id	SWS_FT_FI3
Number of Residues	22
Details	Repeat: {"description":"BNR 3"}

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site_id	SWS_FT_FI4
Number of Residues	22
Details	Repeat: {"description":"BNR 4"}

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site_id	SWS_FT_FI5
Number of Residues	6
Details	Motif: {"description":"FRIP motif"}

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site_id	SWS_FT_FI6
Number of Residues	6
Details	Motif: {"description":"Internalization signal"}

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site_id	SWS_FT_FI7
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI8
Number of Residues	4
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

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site_id	SWS_FT_FI9
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI10
Number of Residues	10
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI11
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

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