8DAF
Human SF-1 LBD bound to synthetic agonist 6N-10CA and bacterial phospholipid
Summary for 8DAF
Entry DOI | 10.2210/pdb8daf/pdb |
Descriptor | Steroidogenic factor 1, Nuclear receptor coactivator 2, 10-[(3aR,6S,6aR)-3-phenyl-3a-(1-phenylethenyl)-6-(sulfamoylamino)-1,3a,4,5,6,6a-hexahydropentalen-2-yl]decanoic acid (non-preferred name), ... (5 entities in total) |
Functional Keywords | sf-1, nuclear receptor, ligand, synthetic agonist, nuclear protein, steroidogenic factor-1, nr5a1 |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 62140.51 |
Authors | D'Agostino, E.H.,Cato, M.L.,Ortlund, E.A. (deposition date: 2022-06-13, release date: 2023-06-28, Last modification date: 2023-10-25) |
Primary citation | Cato, M.L.,D'Agostino, E.H.,Spurlin, R.M.,Flynn, A.R.,Cornelison, J.L.,Johnson, A.M.,Fujita, R.A.,Abraham, S.M.,Jui, N.T.,Ortlund, E.A. Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators. J.Biol.Chem., 299:104921-104921, 2023 Cited by PubMed: 37328104DOI: 10.1016/j.jbc.2023.104921 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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