8DAF
Human SF-1 LBD bound to synthetic agonist 6N-10CA and bacterial phospholipid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Steroidogenic factor 1 | polymer | 247 | 28118.6 | 2 | UniProt (Q13285) Pfam (PF00104) | Homo sapiens (human) | SF-1,STF-1,hSF-1,Adrenal 4-binding protein,Fushi tarazu factor homolog 1,Nuclear receptor subfamily 5 group A member 1,Steroid hormone receptor Ad4BP |
| 2 | C, D (C, D) | Nuclear receptor coactivator 2 | polymer | 14 | 1708.9 | 2 | UniProt (Q15596) | Homo sapiens (human) | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | E, G (A, B) | 10-[(3aR,6S,6aR)-3-phenyl-3a-(1-phenylethenyl)-6-(sulfamoylamino)-1,3a,4,5,6,6a-hexahydropentalen-2-yl]decanoic acid (non-preferred name) | non-polymer | 550.8 | 2 | Chemie (IUW) | |||
| 4 | F, H (A, B) | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE | non-polymer | 692.0 | 2 | Chemie (PEF) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, B: 218 - 461 (UniProt: Q13285)
| PDB | External Database | Details |
|---|---|---|
| Ser 215 | - | expression tag |
| Asn 216 | - | expression tag |
| Ala 217 | - | expression tag |
| Ser 247 | Cys 247 | conflict |
| Ser 412 | Cys 412 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59655.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2485.4 | |
| All* | Total formula weight | 62140.5 |
