8C59
CpG specific M.MpeI methyltransferase crystallized in the presence of 5-bromocytosine (converted to 5mC) and 5-methylcytosine containing dsDNA
Summary for 8C59
Entry DOI | 10.2210/pdb8c59/pdb |
Related | 4DA4 4DKJ 8C56 8C57 8C58 |
Descriptor | Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... (9 entities in total) |
Functional Keywords | m.mpei, dna methyltransferase, dna, 5-methylcytosine, 5-bromocytosine, 5brc, 5mc, cpg, transferase |
Biological source | Malacoplasma penetrans HF-2 More |
Total number of polymer chains | 3 |
Total formula weight | 56330.98 |
Authors | Wojciechowski, M.,Czapinska, H.,Krwawicz, J.,Rafalski, D.,Bochtler, M. (deposition date: 2023-01-06, release date: 2024-01-17) |
Primary citation | Wojciechowski, M.,Czapinska, H.,Krwawicz, J.,Rafalski, D.,Bochtler, M. Cytosine analogues as DNA methyltransferase substrates and inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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