8BLP

Human Urea Transporter UT-B/UT1 in Complex with Inhibitor UTBinh-14

8BLP の概要

• エントリーDOI: 10.2210/pdb8blp/pdb
• EMDBエントリー: 16110 16111 16112
• 分子名称: Urea transporter 1, PHOSPHATIDYLETHANOLAMINE, DODECYL-BETA-D-MALTOSIDE, ... (6 entities in total)
• 機能のキーワード: slc14a1, ut1, ut-b, urea transporter, inhibitor, solute carrier, transport protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 155171.46

構造登録者

Chi, G.,Dietz, L.,Pike, A.C.W.,Maclean, E.M.,Mukhopadhyay, S.M.M.,Bohstedt, T.,Wang, D.,Scacioc, A.,McKinley, G.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Fernandez-Cid, A.,Burgess-Brown, N.A.,Duerr, K.L. (登録日: 2022-11-10, 公開日: 2023-10-04, 最終更新日: 2023-10-11)

• 主引用文献: Chi, G.,Dietz, L.,Tang, H.,Snee, M.,Scacioc, A.,Wang, D.,Mckinley, G.,Mukhopadhyay, S.M.M.,Pike, A.C.W.,Chalk, R.,Burgess-Brown, N.A.,Timmermans, J.P.,van Putte, W.,Robinson, C.V.,Durr, K.L.; Structural characterization of human urea transporters UT-A and UT-B and their inhibition.; Sci Adv, 9:eadg8229-eadg8229, 2023; PubMed: 37774028; DOI: 10.1126/sciadv.adg8229

実験手法

ELECTRON MICROSCOPY (2.6 Å)