8B4F

Crystal structure of human cathepsin L forming a thiohemiacetal with N-Boc-2-aminoacetaldehyde

Summary for 8B4F

• Entry DOI: 10.2210/pdb8b4f/pdb
• Related: 7ZS7 7ZVF 8A5B 8AHV
• Descriptor: Cathepsin L, ~{tert}-butyl ~{N}-(2-hydroxyethyl)carbamate, TRIETHYLENE GLYCOL, ... (8 entities in total)
• Functional Keywords: cystein protease, drug target, lysosome, virus cell entry, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 99196.67

Authors

Falke, S.,Lieske, J.,Guenther, S.,Reinke, P.Y.A.,Ewert, W.,Loboda, J.,Karnicar, K.,Usenik, A.,Lindic, N.,Sekirnik, A.,Chapman, H.N.,Hinrichs, W.,Turk, D.,Meents, A. (deposition date: 2022-09-20, release date: 2023-09-27)

• Primary citation: Falke, S.,Lieske, J.,Herrmann, A.,Guenther, S.,Reinke, P.Y.A.,Ewert, W.,Loboda, J.,Karnicar, K.,Usenik, A.,Lindic, N.,Sekirnik, A.,Chapman, H.N.,Hinrichs, W.,Ebert, G.,Turk, D.,Meents, A.; Crystal structure of human cathepsin L forming a thiohemiacetal with N-Boc-2-aminoacetaldehyde; To be published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)