8A5W

Crystal structure of the human phosphoserine aminotransferase (PSAT) in complex with O-phosphoserine

Summary for 8A5W

• Entry DOI: 10.2210/pdb8a5w/pdb
• Descriptor: Phosphoserine aminotransferase, (2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-phosphonooxy-propanoic acid, (2~{S})-2-[[(~{R})-[[(5~{S})-5-azanyl-6-oxidanylidene-hexyl]amino]-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl]amino]-3-phosphonooxy-propanoic acid, ... (9 entities in total)
• Functional Keywords: transferase, human, psat
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 325450.39

Authors

Costanzi, E.,Demitri, N.,Ullah, R.,Marchesan, F.,Peracchi, A.,Zangelmi, E.,Storici, P.,Campanini, B. (deposition date: 2022-06-16, release date: 2023-03-29, Last modification date: 2024-02-07)

• Primary citation: Marchesani, F.,Zangelmi, E.,Murtas, G.,Costanzi, E.,Ullah, R.,Peracchi, A.,Bruno, S.,Pollegioni, L.,Mozzarelli, A.,Storici, P.,Campanini, B.; L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase.; Protein Sci., 32:e4609-e4609, 2023; PubMed: 36851825; DOI: 10.1002/pro.4609

Experimental method

X-RAY DIFFRACTION (2.78 Å)