8A5W

Crystal structure of the human phosphoserine aminotransferase (PSAT) in complex with O-phosphoserine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, F (D, F, A)	Phosphoserine aminotransferase	polymer	365	39894.9	3	UniProt (Q9Y617) Pfam (PF00266)	Homo sapiens (human)	Phosphohydroxythreonine aminotransferase,PSAT
2	B, C, D, G, H (E, C, B, G, H)	Phosphoserine aminotransferase	polymer	393	43133.4	5	UniProt (Q9Y617) Pfam (PF00266)	Homo sapiens (human)	Phosphohydroxythreonine aminotransferase,PSAT
3	I, N (D, F)	(2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-phosphonooxy-propanoic acid	non-polymer		414.2	2	Chemie (E1U)
4	J, K, L, M (E, C, B)	PHOSPHOSERINE	non-polymer		185.1	4	Chemie (SEP)
5	O (A)	4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE	non-polymer		248.2	1	Chemie (PMP)
6	P, Q (G, H)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
7	R, S, T, U, V... (D, E, C, B, F...)	water	water		18.0	114	Chemie (HOH)

Sequence modifications

E, C, B, G, H: 1 - 370 (UniProt: Q9Y617)

PDB	External Database	Details
Met -22	-	initiating methionine
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Ile -2	-	expression tag
Gly -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	335351.6
Non-Polymers*	Number of molecules	9
	Total formula weight	2009.0
All*	Total formula weight	337360.5

*Water molecules are not included.