8A5W
Crystal structure of the human phosphoserine aminotransferase (PSAT) in complex with O-phosphoserine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | D, F, A | Phosphoserine aminotransferase | polymer | 365 | 39894.9 | 3 | UniProt (Q9Y617) Pfam (PF00266) In PDB | Homo sapiens (human) | Phosphohydroxythreonine aminotransferase,PSAT |
| 2 | E | Phosphoserine aminotransferase | polymer | 393 | 42905.3 | 1 | UniProt (Q9Y617) Pfam (PF00266) In PDB | Homo sapiens (human) | Phosphohydroxythreonine aminotransferase,PSAT |
| 3 | C, B, G, H | Phosphoserine aminotransferase | polymer | 365 | 40123.0 | 4 | UniProt (Q9Y617) Pfam (PF00266) In PDB | Homo sapiens (human) | Phosphohydroxythreonine aminotransferase,PSAT |
| 4 | D, F | (2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-phosphonooxy-propanoic acid | non-polymer | 414.2 | 2 | Chemie (E1U) | |||
| 5 | E | (2~{S})-2-[[(~{R})-[[(5~{S})-5-azanyl-6-oxidanylidene-hexyl]amino]-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl]amino]-3-phosphonooxy-propanoic acid | non-polymer | 544.4 | 1 | Chemie (U93) | |||
| 6 | C, B | PHOSPHOSERINE | non-polymer | 185.1 | 3 | Chemie (SEP) | |||
| 7 | A | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE | non-polymer | 248.2 | 1 | Chemie (PMP) | |||
| 8 | G, H | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 9 | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
E: 1 - 370 (UniProt: Q9Y617)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Ser -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Val -8 | - | expression tag |
| Pro -7 | - | expression tag |
| Arg -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 323082.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2368.3 | |
| All* | Total formula weight | 325450.4 |
