8A0Z

Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and pyrimethamine

Summary for 8A0Z

• Entry DOI: 10.2210/pdb8a0z/pdb
• Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, ... (6 entities in total)
• Functional Keywords: dihydrofolate reductase candida auris nadph pyrimethamine, hydrolase
• Biological source: [Candida] auris
• Total number of polymer chains: 2
• Total formula weight: 49857.16

Authors

Kirkman, T.K.,Dias, M.V.B. (deposition date: 2022-05-30, release date: 2023-06-14, Last modification date: 2024-02-07)

• Primary citation: Kirkman, T.K.,Dias, M.V.B.; Crystal structure of candida auris; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)