8A0Z
Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH and pyrimethamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Dihydrofolate reductase | polymer | 204 | 23634.1 | 2 | UniProt (A0A0L0P1H8) Pfam (PF00186) | [Candida] auris | |
| 2 | C, G (B, A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, H (B, A) | 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE | non-polymer | 248.7 | 2 | Chemie (CP6) | |||
| 4 | E, J (B, A) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 5 | F, I (B, A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 6 | K, L (B, A) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47268.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2588.9 | |
| All* | Total formula weight | 49857.2 |
