8SPN
Crystal structure of macrophage migration inhibitory factor in complex with T614
Summary for 8SPN
Entry DOI | 10.2210/pdb8spn/pdb |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ... (6 entities in total) |
Functional Keywords | inhibitor, enzyme, complex, isomerase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 37783.85 |
Authors | |
Primary citation | Bloom, J.,Pantouris, G.,He, M.,Aljabari, B.,Mishra, L.,Manjula, R.,Parkins, A.,Lolis, E.J.,Al-Abed, Y. Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose. Mol Med, 30:43-43, 2024 Cited by PubMed: 38539088DOI: 10.1186/s10020-024-00803-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
Download full validation report