8PM3
Crystal structure of MAP2K6 with a covalent compound GCL94
Summary for 8PM3
Entry DOI | 10.2210/pdb8pm3/pdb |
Descriptor | Dual specificity mitogen-activated protein kinase kinase 6, ~{N}-[3-(2-azanylpyridin-4-yl)phenyl]propanamide (3 entities in total) |
Functional Keywords | kinase, covalent, inhibitor, map2k6, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 131964.69 |
Authors | Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-06-28, release date: 2023-09-20) |
Primary citation | Wang, G.Q.,Seidler, N.,Roehm, S.,Gehringer, M.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of MAP2K6 with a covalent compound GCL94 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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