8J6K
Crystal structure of pro-interleukin-18 and caspase-4 complex
This is a non-PDB format compatible entry.
Summary for 8J6K
Entry DOI | 10.2210/pdb8j6k/pdb |
Descriptor | Caspase-4 subunit p20, Caspase-4 subunit p10, Interleukin-18, ... (4 entities in total) |
Functional Keywords | inflammatory cytokine, enzyme, immune system, hydrolase-immune system complex, hydrolase/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 70557.54 |
Authors | |
Primary citation | Shi, X.,Sun, Q.,Hou, Y.,Zeng, H.,Cao, Y.,Dong, M.,Ding, J.,Shao, F. Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome. Nature, 624:442-450, 2023 Cited by PubMed: 37993714DOI: 10.1038/s41586-023-06742-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.12 Å) |
Structure validation
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