8GNK
CryoEM structure of cytosol-facing, substrate-bound ratGAT1
Summary for 8GNK
Entry DOI | 10.2210/pdb8gnk/pdb |
EMDB information | 34167 |
Descriptor | Sodium- and chloride-dependent GABA transporter 1, Fragment antigen binding light chain, fragment antigen binding 9D5 heavy chain, ... (10 entities in total) |
Functional Keywords | neurotransmitter sodium symporter, gaba transporter, solute carrier 6, secondary active transport, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 3 |
Total formula weight | 113784.63 |
Authors | Nayak, S.R.,Joseph, D.,Penmatsa, A. (deposition date: 2022-08-24, release date: 2023-05-31, Last modification date: 2023-11-15) |
Primary citation | Nayak, S.R.,Joseph, D.,Hofner, G.,Dakua, A.,Athreya, A.,Wanner, K.T.,Kanner, B.I.,Penmatsa, A. Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism. Nat.Struct.Mol.Biol., 30:1023-1032, 2023 Cited by PubMed: 37400654DOI: 10.1038/s41594-023-01011-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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