8GH4
Complex of Adam 10 disentegrin cysteine rich domains with human monoclonal antibody
Summary for 8GH4
Entry DOI | 10.2210/pdb8gh4/pdb |
Descriptor | Antibody heavy chain, Antibody light chain, Disintegrin and metalloproteinase domain-containing protein 10, ... (4 entities in total) |
Functional Keywords | colorectal cancer, adam 10, human monoclonal antibody, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 68906.23 |
Authors | |
Primary citation | Saha, N.,Baek, D.S.,Mendoza, R.P.,Robev, D.,Xu, Y.,Goldgur, Y.,De La Cruz, M.J.,de Stanchina, E.,Janes, P.W.,Xu, K.,Dimitrov, D.S.,Nikolov, D.B. Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells. Biomed Pharmacother, 161:114494-114494, 2023 Cited by PubMed: 36917886DOI: 10.1016/j.biopha.2023.114494 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
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