8CAF
N8C_Fab3b in complex with NEDD8-CUL1(WHB)
Summary for 8CAF
Entry DOI | 10.2210/pdb8caf/pdb |
Descriptor | Fab Light Chain, Fab Heavy Chain, Cullin-1, ... (4 entities in total) |
Functional Keywords | nedd8, cullin-ring ligase, ubiquitin, antibody, cell cycle |
Biological source | Homo sapiens More |
Total number of polymer chains | 8 |
Total formula weight | 128531.14 |
Authors | Duda, D.M.,Yanishevski, D.,Henneberg, L.T.,Schulman, B.A. (deposition date: 2023-01-24, release date: 2023-09-13, Last modification date: 2023-12-06) |
Primary citation | Henneberg, L.T.,Singh, J.,Duda, D.M.,Baek, K.,Yanishevski, D.,Murray, P.J.,Mann, M.,Sidhu, S.S.,Schulman, B.A. Activity-based profiling of cullin-RING E3 networks by conformation-specific probes. Nat.Chem.Biol., 19:1513-1523, 2023 Cited by PubMed: 37653169DOI: 10.1038/s41589-023-01392-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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