8ACF
Structure of the argX-117 in complex with a complement C2 fragment at low pH
Summary for 8ACF
Entry DOI | 10.2210/pdb8acf/pdb |
Descriptor | Complement C2b fragment, Heavy chain of mAb ARGX-117 Fab, Nanobody specific for the kappa-light chain, ... (9 entities in total) |
Functional Keywords | innate immune system, complement, antibody, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 83939.91 |
Authors | |
Primary citation | Olesen, H.G.,Andersen, G.R. Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody To be published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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