8ACF
Structure of the argX-117 in complex with a complement C2 fragment at low pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Complement C2b fragment | polymer | 197 | 20991.4 | 1 | UniProt (P06681) Pfam (PF00084) | Homo sapiens (human) | |
| 2 | B (H) | Heavy chain of mAb ARGX-117 Fab | polymer | 219 | 23450.1 | 1 | Homo sapiens (Human) | ||
| 3 | C (K) | Nanobody specific for the kappa-light chain | polymer | 128 | 14204.5 | 1 | Lama glama | ||
| 4 | D (L) | Light chain of mAb ARGX-117 Fab | polymer | 218 | 23957.6 | 1 | Homo sapiens (Human) | ||
| 5 | E (X) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 6 | F, I (A, L) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 7 | G (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | H, J (K, L) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | K, L, M, N (A, H, K, L) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 82603.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 587.6 | |
| All* | Total formula weight | 83939.9 |
