7ZTV
Crystal structure of mutant AR-LBD (F755L) bound to dihydrotestosterone
Summary for 7ZTV
Entry DOI | 10.2210/pdb7ztv/pdb |
Related | 7ZTX 7ZTZ 7ZU1 7ZU2 |
Descriptor | Androgen receptor, 5-ALPHA-DIHYDROTESTOSTERONE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | hormone receptor, nuclear receptor, dht receptor, dna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 29364.57 |
Authors | Alegre-Marti, A.,Jimenez-Panizo, A.,Estebanez-Perpina, E.,Fuentes-Prior, P. (deposition date: 2022-05-11, release date: 2023-03-22, Last modification date: 2024-02-07) |
Primary citation | Alegre-Marti, A.,Jimenez-Panizo, A.,Martinez-Tebar, A.,Poulard, C.,Peralta-Moreno, M.N.,Abella, M.,Anton, R.,Chinas, M.,Eckhard, U.,Piulats, J.M.,Rojas, A.M.,Fernandez-Recio, J.,Rubio-Martinez, J.,Le Romancer, M.,Aytes, A.,Fuentes-Prior, P.,Estebanez-Perpina, E. A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance. Sci Adv, 9:eade2175-eade2175, 2023 Cited by PubMed: 36921044DOI: 10.1126/sciadv.ade2175 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
Download full validation report