7ZTV
Crystal structure of mutant AR-LBD (F755L) bound to dihydrotestosterone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 249 | 29012.1 | 1 | UniProt (P15207) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A: 672 - 920 (UniProt: P15207)
| PDB | External Database | Details |
|---|---|---|
| Leu 755 | Phe 737 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29012.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 352.5 | |
| All* | Total formula weight | 29364.6 |
