7Z3J

Structure of crystallisable rat Phospholipase C gamma 1 in complex with inositol 1,4,5-trisphosphate

7Z3J の概要

• エントリーDOI: 10.2210/pdb7z3j/pdb
• 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: hydrolase complex autoinhibited state, hydrolase
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 136767.47

構造登録者

Pinotsis, N.,Bunney, T.D.,Katan, M. (登録日: 2022-03-02, 公開日: 2022-07-20, 最終更新日: 2024-01-31)

• 主引用文献: Le Huray, K.I.P.,Bunney, T.D.,Pinotsis, N.,Kalli, A.C.,Katan, M.; Characterization of the membrane interactions of phospholipase C gamma reveals key features of the active enzyme.; Sci Adv, 8:eabp9688-eabp9688, 2022; PubMed: 35749497; DOI: 10.1126/sciadv.abp9688

実験手法

X-RAY DIFFRACTION (2 Å)