7Z13
S. cerevisiae CMGE dimer nucleating origin DNA melting
This is a non-PDB format compatible entry.
Summary for 7Z13
Entry DOI | 10.2210/pdb7z13/pdb |
Related | 7QHS |
EMDB information | 14439 |
Descriptor | DNA replication licensing factor MCM2, DNA replication complex GINS protein SLD5, Cell division control protein 45, ... (19 entities in total) |
Functional Keywords | dna replication, helicase, initiation, dna origin, replication |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Total number of polymer chains | 28 |
Total formula weight | 2297536.23 |
Authors | Lewis, J.S.,Sousa, J.S.,Costa, A. (deposition date: 2022-02-24, release date: 2022-06-15, Last modification date: 2024-07-17) |
Primary citation | Lewis, J.S.,Gross, M.H.,Sousa, J.,Henrikus, S.S.,Greiwe, J.F.,Nans, A.,Diffley, J.F.X.,Costa, A. Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606:1007-1014, 2022 Cited by PubMed: 35705812DOI: 10.1038/s41586-022-04829-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
Download full validation report