7UL2
CryoEM Structure of Inactive NTSR1 Bound to SR48692 and Nb6
Summary for 7UL2
Entry DOI | 10.2210/pdb7ul2/pdb |
EMDB information | 26589 |
Descriptor | Neurotensin receptor 1, Nanobody 6, 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, ... (5 entities in total) |
Functional Keywords | antagonist, complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 62424.70 |
Authors | Robertson, M.J.,Skiniotis, G. (deposition date: 2022-04-03, release date: 2022-06-29, Last modification date: 2024-09-25) |
Primary citation | Robertson, M.J.,Papasergi-Scott, M.M.,He, F.,Seven, A.B.,Meyerowitz, J.G.,Panova, O.,Peroto, M.C.,Che, T.,Skiniotis, G. Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29:1188-1195, 2022 Cited by PubMed: 36396979DOI: 10.1038/s41594-022-00859-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.4 Å) |
Structure validation
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