7U24
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation
Summary for 7U24
Entry DOI | 10.2210/pdb7u24/pdb |
Related | 6PZA 7TYS 7TYT 7U1Q 7U1S |
EMDB information | 20530 26307 |
Descriptor | ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8, ADENOSINE-5'-TRIPHOSPHATE, ... (8 entities in total) |
Functional Keywords | katp channel, sur1, kir6.2, glibenclamide, gbc, gbm, sulfonylurea receptor, potassium transport, metabolic sensor, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 5 |
Total formula weight | 369070.92 |
Authors | Shyng, S.L.,Sung, M.W.,Driggers, C.M. (deposition date: 2022-02-23, release date: 2022-08-31, Last modification date: 2022-09-14) |
Primary citation | Sung, M.W.,Driggers, C.M.,Mostofian, B.,Russo, J.D.,Patton, B.L.,Zuckerman, D.M.,Shyng, S.L. Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434:167789-167789, 2022 Cited by PubMed: 35964676DOI: 10.1016/j.jmb.2022.167789 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.58 Å) |
Structure validation
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