7TPB
p120RasGAP SH3 domain in complex with DLC1 RhoGAP domain
Summary for 7TPB
| Entry DOI | 10.2210/pdb7tpb/pdb |
| Descriptor | Ras GTPase-activating protein 1, Rho GTPase-activating protein 7 (2 entities in total) |
| Functional Keywords | sh3 domain, rhogap domain, complex, gtpase, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 134646.24 |
| Authors | Stiegler, A.L.,Boggon, T.J.,Chau, J.E.,Vish, K.J. (deposition date: 2022-01-25, release date: 2022-08-03, Last modification date: 2023-10-18) |
| Primary citation | Chau, J.E.,Vish, K.J.,Boggon, T.J.,Stiegler, A.L. SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP. Nat Commun, 13:4788-4788, 2022 Cited by PubMed: 35970859DOI: 10.1038/s41467-022-32541-4 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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