7TPB

p120RasGAP SH3 domain in complex with DLC1 RhoGAP domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Ras GTPase-activating protein 1	polymer	66	7622.6	4	UniProt (B4DTL8) Pfam (PF00018) In PDB	Homo sapiens (human)
2	B, D, F, H	Rho GTPase-activating protein 7	polymer	228	26038.9	4	UniProt (Q96QB1-6) In PDB	Homo sapiens (human)	Deleted in liver cancer 1 protein,DLC-1,HP protein,Rho-type GTPase-activating protein 7,START domain-containing protein 12,StARD12,StAR-related lipid transfer protein 12

Sequence modifications

A, C, E, G: 281 - 341 (UniProt: B4DTL8)

PDB	External Database	Details
Gly 276	-	expression tag
Pro 277	-	expression tag
Leu 278	-	expression tag
Gly 279	-	expression tag
Ser 280	-	expression tag

B, D, F, H: 1074 - 1283 (UniProt: Q96QB1-6)

PDB	External Database	Details
Met 1056	-	initiating methionine
His 1057	-	expression tag
His 1058	-	expression tag
His 1059	-	expression tag
His 1060	-	expression tag
His 1061	-	expression tag
His 1062	-	expression tag
Ser 1063	-	expression tag
Ser 1064	-	expression tag
Gly 1065	-	expression tag
Arg 1066	-	expression tag
Glu 1067	-	expression tag
Asn 1068	-	expression tag
Leu 1069	-	expression tag
Tyr 1070	-	expression tag
Phe 1071	-	expression tag
Gln 1072	-	expression tag
Gly 1073	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	134646.2
All*	Total formula weight	134646.2

*Water molecules are not included.