7TN9

Structure of the Inmazeb cocktail and resistance to escape against Ebola virus

Summary for 7TN9

Entry DOI	10.2210/pdb7tn9/pdb
EMDB information	26005
Descriptor	REGN3471 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... (10 entities in total)
Functional Keywords	ebola, antiviral, therapeutics, immune system-viral protein complex, immune system/viral protein
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	22
Total formula weight	532354.04
Authors	Rayaprolu, V.,Fulton, B.,Rafique, A.,Arturo, E.,Williams, D.,Hariharan, C.,Callaway, H.,Parvate, A.,Schendel, S.L.,Parekh, D.,Hui, S.,Shaffer, K.,Pascal, K.E.,Wloga, E.,Giordano, S.,Copin, R.,Franklin, M.,Boytz, R.M.,Donahue, C.,Davey, R.,Baum, A.,Kyratsous, C.A.,Saphire, E.O. (deposition date: 2022-01-20, release date: 2023-01-25, Last modification date: 2023-02-22)
Primary citation	Rayaprolu, V.,Fulton, B.O.,Rafique, A.,Arturo, E.,Williams, D.,Hariharan, C.,Callaway, H.,Parvate, A.,Schendel, S.L.,Parekh, D.,Hui, S.,Shaffer, K.,Pascal, K.E.,Wloga, E.,Giordano, S.,Negron, N.,Ni, M.,Copin, R.,Atwal, G.S.,Franklin, M.,Boytz, R.M.,Donahue, C.,Davey, R.,Baum, A.,Kyratsous, C.A.,Saphire, E.O. Structure of the Inmazeb cocktail and resistance to Ebola virus escape. Cell Host Microbe, 31:260-, 2023 Cited by PubMed: 36708708 DOI: 10.1016/j.chom.2023.01.002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation