7TN9
Structure of the Inmazeb cocktail and resistance to escape against Ebola virus
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| G | TYR197-HIS203 | |
| A | TYR199-HIS205 | |
| F | TYR198-HIS204 | |
| R | TYR191-HIS197 | |
| H | TYR193-HIS199 | |
| Q | TYR199-HIS205 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host ADAM17 => ECO:0000269|PubMed:15103332 |
| Chain | Residue | Details |
| W | ASP637 | |
| S | PHE88 | |
| S | LYS95 | |
| S | ILE170 | |
| U | LEU57 | |
| U | LEU63 | |
| U | ARG64 | |
| U | PHE88 | |
| U | LYS95 | |
| U | ILE170 | |
| V | ASP637 | |
| X | ASP637 | |
| T | PHE88 | |
| T | LYS95 | |
| T | ILE170 | |
| S | LEU57 | |
| S | LEU63 | |
| S | ARG64 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255 |
| Chain | Residue | Details |
| W | ASN563 | |
| S | ASN228 | |
| S | ASN238 | |
| S | ASN257 | |
| S | ASN268 | |
| S | ASN296 | |
| U | ASN40 | |
| U | ASN204 | |
| U | ASN228 | |
| U | ASN238 | |
| U | ASN257 | |
| W | ASN618 | |
| U | ASN268 | |
| U | ASN296 | |
| V | ASN563 | |
| V | ASN618 | |
| X | ASN563 | |
| X | ASN618 | |
| T | ASN296 | |
| S | ASN40 | |
| S | ASN204 |
