7T8W

Structure of antibody 3G12 bound to Respiratory Syncytial Virus G central conserved domain mutant S177Q

Summary for 7T8W

Entry DOI	10.2210/pdb7t8w/pdb
Descriptor	3G12 Fab Light chain, 3G12 Fab Heavy chain, Mature secreted glycoprotein G (3 entities in total)
Functional Keywords	respiratory syncytial virus, human antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	53834.27
Authors	Nunez Castrejon, A.M.,O'Rourke, S.M.,Kauvar, L.M.,DuBois, R.M. (deposition date: 2021-12-17, release date: 2022-02-09, Last modification date: 2023-10-18)
Primary citation	Nunez Castrejon, A.M.,O'Rourke, S.M.,Kauvar, L.M.,DuBois, R.M. Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens. J.Virol., 96:e0220121-e0220121, 2022 Cited by PubMed: 35266806 DOI: 10.1128/jvi.02201-21 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation