7T8W
Structure of antibody 3G12 bound to Respiratory Syncytial Virus G central conserved domain mutant S177Q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | 3G12 Fab Light chain | polymer | 213 | 23218.8 | 1 | Homo sapiens (Human) | ||
| 2 | B (H) | 3G12 Fab Heavy chain | polymer | 232 | 24838.8 | 1 | Homo sapiens (Human) | ||
| 3 | C (D) | Mature secreted glycoprotein G | polymer | 49 | 5776.7 | 1 | UniProt (P03423) | Human respiratory syncytial virus A2 | Mature sG |
Sequence modifications
D: 157 - 197 (UniProt: P03423)
| PDB | External Database | Details |
|---|---|---|
| Met 155 | - | initiating methionine |
| Gly 156 | - | expression tag |
| Gln 177 | Ser 177 | engineered mutation |
| His 198 | - | expression tag |
| His 199 | - | expression tag |
| His 200 | - | expression tag |
| His 201 | - | expression tag |
| His 202 | - | expression tag |
| His 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 53834.3 | |
| All* | Total formula weight | 53834.3 |
