7T0S

Crystal structure of the BCL6 BTB domain in complex with OICR-11864

Summary for 7T0S

• Entry DOI: 10.2210/pdb7t0s/pdb
• Related: 7LWE 7LWF 7LWG 7LZQ 7LZS 7RUW 7RUX 7RUY 7RUZ 7RV0 7RV1 7RV2 7RV3 7RV4 7RV5 7RV6 7RV7 7RV8 7RV9
• Descriptor: Isoform 2 of B-cell lymphoma 6 protein, 3-chloro-5-{1-[2-({5-chloro-2-[(3S)-3-methylmorpholin-4-yl]pyridin-4-yl}amino)-2-oxoethyl]-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}-2-hydroxybenzamide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: immunity, inflammatory response, transcription repressor, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 45619.32

Authors

Kuntz, D.A.,Prive, G.G. (deposition date: 2021-11-30, release date: 2022-12-14, Last modification date: 2023-10-25)

• Primary citation: Kuntz, D.A.,Prive, G.G.; Crystal structure of the BCL6 BTB domain in complex with OICR-11864; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.86 Å)