7RV4

Crystal structure of the BCL6 BTB domain in complex with OICR-9153

Summary for 7RV4

• Entry DOI: 10.2210/pdb7rv4/pdb
• Related: 7LWE 7LWF 7LWG
• Descriptor: Isoform 2 of B-cell lymphoma 6 protein, N-(3-chloropyridin-4-yl)-2-{5-(3-cyanophenyl)-3-[3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl]-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}acetamide, DIMETHYL SULFOXIDE, ... (6 entities in total)
• Functional Keywords: immunity, inflammatory response, transcription repressor, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 15423.93

Authors

Kuntz, D.A.,Prive, G.G. (deposition date: 2021-08-18, release date: 2022-08-24, Last modification date: 2024-04-03)

• Primary citation: Watson, I.,Isaac, M.; Structure of the BCL6 BTB domain; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.25 Å)