7T0S
Crystal structure of the BCL6 BTB domain in complex with OICR-11864
Summary for 7T0S
Entry DOI | 10.2210/pdb7t0s/pdb |
Related | 7LWE 7LWF 7LWG 7LZQ 7LZS 7RUW 7RUX 7RUY 7RUZ 7RV0 7RV1 7RV2 7RV3 7RV4 7RV5 7RV6 7RV7 7RV8 7RV9 |
Descriptor | Isoform 2 of B-cell lymphoma 6 protein, 3-chloro-5-{1-[2-({5-chloro-2-[(3S)-3-methylmorpholin-4-yl]pyridin-4-yl}amino)-2-oxoethyl]-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}-2-hydroxybenzamide, GLYCEROL, ... (5 entities in total) |
Functional Keywords | immunity, inflammatory response, transcription repressor, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 45619.32 |
Authors | Kuntz, D.A.,Prive, G.G. (deposition date: 2021-11-30, release date: 2022-12-14, Last modification date: 2023-10-25) |
Primary citation | Kuntz, D.A.,Prive, G.G. Crystal structure of the BCL6 BTB domain in complex with OICR-11864 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
Download full validation report