7RV1
Crystal structure of the BCL6 BTB domain in complex with OICR-8826
Summary for 7RV1
Entry DOI | 10.2210/pdb7rv1/pdb |
Related | 7LWE 7LWF 7LWG |
Descriptor | B-cell lymphoma 6 protein, (E)-3-(7-(2-((3-chloropyridin-4-yl)amino)-2-oxoethyl)-3-(3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)acrylamide, SULFATE ION, ... (5 entities in total) |
Functional Keywords | immunity, inflammatory response, transcription repressor, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15320.98 |
Authors | Kuntz, D.A.,Prive, G.G. (deposition date: 2021-08-18, release date: 2022-11-09, Last modification date: 2023-10-18) |
Primary citation | Watson, I.,Isaac, M. Crystal structure of the BCL6 BTB domain in complex with OICR-8826 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.17 Å) |
Structure validation
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