7SI4

CRYSTAL STRUCTURE OF EED WITH MRTX-2219

Summary for 7SI4

• Entry DOI: 10.2210/pdb7si4/pdb
• Descriptor: Polycomb protein EED, (4S)-8-{4-[(dimethylamino)methyl]-2-methylphenyl}-5-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}imidazo[1,2-c]pyrimidine-2-carbonitrile, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: eed, oncology, transcription-transferase, gene regulation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 46706.91

Authors

Gunn, R.J.,Burns, A.C.,Lawson, J.D.,Marx, M.A. (deposition date: 2021-10-12, release date: 2022-11-09, Last modification date: 2023-10-18)

• Primary citation: Burns, A.C.; CRYSTAL STRUCTURE OF EED WITH MRTX-2219; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.9 Å)