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7SI4

CRYSTAL STRUCTURE OF EED WITH MRTX-2219

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Polycomb protein EEDpolymer40246158.31UniProt (O75530)
Pfam (PF00400)
Homo sapiens (Human)hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1
2B
(A)
(4S)-8-{4-[(dimethylamino)methyl]-2-methylphenyl}-5-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}imidazo[1,2-c]pyrimidine-2-carbonitrilenon-polymer456.51Chemie (9JL)
3C, D
(A)
FORMIC ACIDnon-polymer46.02Chemie (FMT)
4E
(A)
waterwater18.0323Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight46158.3
Non-Polymers*Number of molecules3
Total formula weight548.6
All*Total formula weight46706.9
*Water molecules are not included.

227561

PDB entries from 2024-11-20

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