7SI4
CRYSTAL STRUCTURE OF EED WITH MRTX-2219
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Polycomb protein EED | polymer | 402 | 46158.3 | 1 | UniProt (O75530) Pfam (PF00400) In PDB | Homo sapiens (Human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 2 | A | (4S)-8-{4-[(dimethylamino)methyl]-2-methylphenyl}-5-{[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]amino}imidazo[1,2-c]pyrimidine-2-carbonitrile | non-polymer | 456.5 | 1 | Chemie (9JL) | |||
| 3 | A | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 4 | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46158.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 548.6 | |
| All* | Total formula weight | 46706.9 |
