7RE7

TCR mimic antibody (Fab fragment) in complex with AFP/HLA-A*02

7RE7 の概要

• エントリーDOI: 10.2210/pdb7re7/pdb
• 分子名称: Fab heavy chain, TRIETHYLENE GLYCOL, PENTAETHYLENE GLYCOL, ... (13 entities in total)
• 機能のキーワード: tcr mimic antibody (fab fragment), class i major histocompatibility complex (hla-a*02), alpha fetoprotein peptide., immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 190966.27

構造登録者

Dasgupta, M.,Baker, B.M. (登録日: 2021-07-12, 公開日: 2022-07-27, 最終更新日: 2023-10-18)

• 主引用文献: Liu, C.,Liu, H.,Dasgupta, M.,Hellman, L.M.,Zhang, X.,Qu, K.,Xue, H.,Wang, Y.,Fan, F.,Chang, Q.,Yu, D.,Ge, L.,Zhang, Y.,Cui, Z.,Zhang, P.,Heller, B.,Zhang, H.,Shi, B.,Baker, B.M.,Liu, C.; Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.; Sci Rep, 12:12068-12068, 2022; PubMed: 35840635; DOI: 10.1038/s41598-022-15946-5

実験手法

X-RAY DIFFRACTION (2.547 Å)