7RAV
Cryo-EM structure of the unliganded form of NLR family apoptosis inhibitory protein 5 (NAIP5)
Summary for 7RAV
| Entry DOI | 10.2210/pdb7rav/pdb |
| EMDB information | 24387 |
| Descriptor | Baculoviral IAP repeat-containing protein 1e, ADENOSINE-5'-TRIPHOSPHATE (2 entities in total) |
| Functional Keywords | pre-liganded naip5, inflammasome, innate immunity, host-pathogen interaction, immune system |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 161635.34 |
| Authors | Paidimuddala, B.,Cao, J.,Xie, Q.,Wu, H.,Zhang, L. (deposition date: 2021-07-02, release date: 2023-01-11, Last modification date: 2023-03-01) |
| Primary citation | Paidimuddala, B.,Cao, J.,Nash, G.,Xie, Q.,Wu, H.,Zhang, L. Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. Nat.Struct.Mol.Biol., 30:159-166, 2023 Cited by PubMed: 36604500DOI: 10.1038/s41594-022-00889-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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