7QPI

Structure of lamprey VDR in complex with 1,25D3

Summary for 7QPI

Entry DOI	10.2210/pdb7qpi/pdb
Descriptor	Vitamin D receptor, Nuclear receptor coactivator 1, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	vdr, complex, agonist, transcription
Biological source	Petromyzon marinus (sea lamprey) More
Total number of polymer chains	2
Total formula weight	34463.16
Authors	Rochel, N. (deposition date: 2022-01-04, release date: 2022-12-14, Last modification date: 2024-01-31)
Primary citation	Sigueiro, R.,Bianchetti, L.,Peluso-Iltis, C.,Chalhoub, S.,Dejaegere, A.,Osz, J.,Rochel, N. Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain. J.Med.Chem., 65:5821-5829, 2022 Cited by PubMed: 35302785 DOI: 10.1021/acs.jmedchem.2c00171 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation