7QID

tentative model of the human insulin receptor ectodomain bound by three insulin

Summary for 7QID

• Entry DOI: 10.2210/pdb7qid/pdb
• Related: 6SOF
• EMDB information: 10273 10311
• Descriptor: Insulin receptor, Isoform Short of Insulin receptor, Insulin, ... (4 entities in total)
• Functional Keywords: cell surface receptor, insulin, tyrosine kinase receptor, glucose homeostasis, hormone, diabetes, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 225810.93

Authors

Gutman, T.,Schaefer, I.B.,Poojari, C.S.,Vattulainen, I.,Strauss, M.,Coskun, U. (deposition date: 2021-12-14, release date: 2022-02-02)

• Primary citation: Gutman, T.,Schaefer, I.B.,Poojari, C.S.,Vattulainen, I.,Strauss, M.,Coskun, U.; Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain; J Cell Biol, 219:-, 2020; PubMed: 31727777

Experimental method

ELECTRON MICROSCOPY (5 Å)