7Q4D
Local refinement structure of the two interacting N-domains of full-length, dimeric, soluble somatic angiotensin I-converting enzyme
Summary for 7Q4D
Entry DOI | 10.2210/pdb7q4d/pdb |
Related | 7Q3Y 7Q49 7Q4C 7Q4E |
EMDB information | 13797 13799 13801 13802 13803 13804 |
Descriptor | Angiotensin-converting enzyme, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | zinc metalloprotease dicarboxypeptidase glycoprotein, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 290090.72 |
Authors | Lubbe, L.,Sewell, B.T.,Sturrock, E.D. (deposition date: 2021-10-30, release date: 2022-07-20, Last modification date: 2022-08-24) |
Primary citation | Lubbe, L.,Sewell, B.T.,Woodward, J.D.,Sturrock, E.D. Cryo-EM reveals mechanisms of angiotensin I-converting enzyme allostery and dimerization. Embo J., 41:e110550-e110550, 2022 Cited by PubMed: 35818993DOI: 10.15252/embj.2021110550 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.78 Å) |
Structure validation
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