7PQH
Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains).
This is a non-PDB format compatible entry.
Summary for 7PQH
Entry DOI | 10.2210/pdb7pqh/pdb |
EMDB information | 13594 13595 |
Descriptor | Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8, Serine/threonine-protein kinase TOR2 (3 entities in total) |
Functional Keywords | target of rapamycin, torc1, kog1, lst8, tor2, frb domain, signaling protein |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Total number of polymer chains | 12 |
Total formula weight | 1998351.52 |
Authors | Felix, J.,Prouteau, M.,Bourgoint, C.,Bonadei, L.,Desfosses, A.,Gabus, C.,Sadian, Y.,Savvides, S.N.,Gutsche, I.,Loewith, R. (deposition date: 2021-09-17, release date: 2023-01-18, Last modification date: 2023-03-29) |
Primary citation | Prouteau, M.,Bourgoint, C.,Felix, J.,Bonadei, L.,Sadian, Y.,Gabus, C.,Savvides, S.N.,Gutsche, I.,Desfosses, A.,Loewith, R. EGOC inhibits TOROID polymerization by structurally activating TORC1. Nat.Struct.Mol.Biol., 30:273-285, 2023 Cited by PubMed: 36702972DOI: 10.1038/s41594-022-00912-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.87 Å) |
Structure validation
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