7PQC
tau-microtubule structural ensemble based on CryoEM data
Summary for 7PQC
Entry DOI | 10.2210/pdb7pqc/pdb |
EMDB information | 7522 |
Descriptor | Tubulin beta chain, Tubulin alpha-1B chain, Isoform Tau-F of Microtubule-associated protein tau, ... (6 entities in total) |
Functional Keywords | complex, structural protein |
Biological source | Sus scrofa (Pig) More |
Total number of polymer chains | 15 |
Total formula weight | 728461.17 |
Authors | Brotzakis, Z.F.,Vendruscolo, M. (deposition date: 2021-09-16, release date: 2021-12-15, Last modification date: 2022-01-12) |
Primary citation | Brotzakis, Z.F.,Lindstedt, P.R.,Taylor, R.J.,Rinauro, D.J.,Gallagher, N.C.T.,Bernardes, G.J.L.,Vendruscolo, M. A Structural Ensemble of a Tau-Microtubule Complex Reveals Regulatory Tau Phosphorylation and Acetylation Mechanisms. Acs Cent.Sci., 7:1986-1995, 2021 Cited by PubMed: 34963892DOI: 10.1021/acscentsci.1c00585 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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