7PQC

tau-microtubule structural ensemble based on CryoEM data

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	Tubulin beta chain	polymer	445	49907.8	7	UniProt (P02554) Pfam (PF00091) Pfam (PF03953) In PDB	Sus scrofa (Pig)	Beta-tubulin
2	B, D, F, H, J...	Tubulin alpha-1B chain	polymer	451	50204.4	7	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB	Sus scrofa (Pig)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
3	O	Isoform Tau-F of Microtubule-associated protein tau	polymer	194	20740.9	1	UniProt (P10636) Pfam (PF00418) In PDB	Homo sapiens (Human)	Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau
4	I, K, M, A, C...	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	7	Chemie (GDP)
5	J, L, N, B, D...	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	7	Chemie (GTP)
6	H, J, L, N, B...	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	15
	Total formula weight	721526.4
Non-Polymers*	Number of molecules	21
	Total formula weight	6934.8
All*	Total formula weight	728461.2

*Water molecules are not included.