7PO6

Xist (m6A)UCG tetraloop RNA bound to the YTH domain of YTHDC1

Summary for 7PO6

• Entry DOI: 10.2210/pdb7po6/pdb
• Descriptor: RNA (5'-R(*(6MZ)P*UP*C)-3'), Isoform 2 of YTH domain-containing protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: m6a, ythdc1, xist, complex, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 72158.33

Authors

Jones, A.N.,Mourao, A.,Sattler, M. (deposition date: 2021-09-08, release date: 2022-03-16, Last modification date: 2024-01-31)

• Primary citation: Jones, A.N.,Tikhaia, E.,Mourao, A.,Sattler, M.; Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1.; Nucleic Acids Res., 50:2350-2362, 2022; PubMed: 35166835; DOI: 10.1093/nar/gkac080

Experimental method

X-RAY DIFFRACTION (1.77 Å)