7PL1
Crystal structure of human METTL1 bound to Sinefungin
Summary for 7PL1
Entry DOI | 10.2210/pdb7pl1/pdb |
Descriptor | tRNA (guanine-N(7)-)-methyltransferase, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
Functional Keywords | methyltranferase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 30154.36 |
Authors | Nai, F.,Caflisch, A. (deposition date: 2021-08-27, release date: 2021-09-15, Last modification date: 2023-12-20) |
Primary citation | Nai, F.,Flores Espinoza, M.P.,Invernizzi, A.,Vargas-Rosales, P.A.,Bobileva, O.,Herok, M.,Caflisch, A. Small-Molecule Inhibitors of the m7G-RNA Writer METTL1 Acs Bio Med Chem Au, 2023 Cited by DOI: 10.1021/acsbiomedchemau.3c00030PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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